Hydrogen Bromide → 3-[5-Cyano-4-[(2,2-dimethyl-propyl)-methyl-amino]-6-(4-methyl-[1,4]diazepan-1-yl)-pyrimidin-2-ylamino]-N-methoxy-4-methyl-benzamide
Reaction equation
[Br:38].[C:39](=[O:40])([OH:41])[O-:42].[CH2:44]([Cl:45])[Cl:46].[CH3:1][C:2]([CH2:3][N:4]([c:5]1[n:6][c:7]([NH:19][c:20]2[cH:21][c:22]([C:23](=[O:24])[NH:25][O:26][CH3:27])[cH:28][cH:29][c:30]2[CH3:31])[n:8][c:9]([N:11]2[CH2:12][CH2:13][N:14]([CH3:18])[CH2:15][CH2:16][CH2:17]2)[cH:10]1)[CH3:32])([CH3:33])[CH3:34].[Na+:43].[Na:35][C:36]#[N:37].[OH2:47]>>[CH3:1][C:2]([CH2:3][N:4]([c:5]1[n:6][c:7]([NH:19][c:20]2[cH:21][c:22]([C:23](=[O:24])[NH:25][O:26][CH3:27])[cH:28][cH:29][c:30]2[CH3:31])[n:8][c:9]([N:11]2[CH2:12][CH2:13][N:14]([CH3:18])[CH2:15][CH2:16][CH2:17]2)[c:10]1[C:36]#[N:37])[CH3:32])([CH3:33])[CH3:34]Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-5ca7649073a34113996243b5d0bd73e8
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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