HuagongsheHuagongshe Chemistry Print Report · For research reference only
(4-(4-Fluorophenyl)-1-methyl-1H-pyrazol-5-yl)methanol → HCID 85969110, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (4-(4-Fluorophenyl)-1-methyl-1H-pyrazol-5-yl)methanol | HCID 69207780 | — |
| Catalyst | HCID 178418406 | HCID 178418406 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 85969110 | HCID 85969110 | 70% |
Reaction Steps
A mixture of [4-(4-fluorophenyl)-1-methyl-1H-pyrazol-5-yl]methanol (250 mg), activated manganese dioxide (1.0 g) and tetrahydrofuran (10 ml) was stirred at room temperature for 3 hrs. The reaction mixture was filtered, and the organic layer was concentrated to give 4-(4-fluorophenyl)-1-methyl-1H-pyrazole-5-carbaldehyde (172 mg, yield 70%) as pale-yellow crystals.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07423159B2 |
| Source dataset | uspto-grants-2008_09 |
| ORD ID | ord-1e93fb7e727246f5890a765717768e33 |
| Source note | uspto-grants-2008_09 |