1,2-Dichloroethane → 8-Bromo-3-(n-propylamino)chroman

HRID 307124Notes

Reaction equation

HRID 307124 reaction equation
[BH4-:18].[Br:1][c:2]1[cH:3][cH:4][cH:5][c:6]2[c:11]1[O:10][CH2:9][CH:8]([NH2:12])[CH2:7]2.[C:13]([CH2:14][CH3:15])([Cl:16])=[O:17].[C:43](=[O:44])([O-:45])[O-:46].[CH2:19]([N+:20]([CH2:21][CH2:22][CH2:23][CH3:24])([CH2:25][CH2:26][CH2:27][CH3:28])[CH2:29][CH2:30][CH2:31][CH3:32])[CH2:33][CH2:34][CH3:35].[Cl:36][CH2:37][CH2:38][Cl:39].[Cl:40][CH2:41][Cl:42].[Na+:47].[Na+:48]>>[Br:1][c:2]1[cH:3][cH:4][cH:5][c:6]2[c:11]1[O:10][CH2:9][CH:8]([NH:12][CH2:13][CH2:14][CH3:15])[CH2:7]2

Participants

9

Reactant 8

HCID 111,2-DichloroethaneHCID 923Sodium ion2×HCID 6344DichloromethaneHCID 16028TetrabutylammoniumHCID 19660Carbonate IonHCID 28123BorohydrideHCID 62324Propionyl chlorideHCID 162444248-Bromo-3,4-dihydro-2H-1-benzopyran-3-amine

Product 1

HCID 190871638-Bromo-3-(n-propylamino)chroman

Sources & evidence

ORD record
ord-7ef0bf4d4a11496e96102bc28e15d360
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

Loading…