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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 30713Generated: October 28, 2026

Hydrochloric Acid → HCID 69205646, compound

https://huagongshe.com/reaction/30713

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantSodium HydroxideHCID 14798—
ReactantN-[4-(ethoxycarbonylmethyl)phenyl]-3-(1,5-diphenyl-1H-pyrazol-4-yl)propionamideHCID 69207828—
SolventEthanolHCID 702—
ProductHCID 69205646HCID 6920564694%

Reaction Steps

A mixture of N-[4-(ethoxycarbonylmethyl)phenyl]-3-(1,5-diphenyl-1H-pyrazol-4-yl)propionamide (0.76 g), a 1N aqueous sodium hydroxide solution (5 ml) and ethanol (5 ml) was stirred at 50° C. for 3 hrs. The reaction mixture was poured into a 1N aqueous hydrochloric acid solution and the precipitated crystals were collected by filtration, washed with water and dried to give (4-{[3-(1,5-diphenyl-1H-pyrazol-4-yl)propanoyl]amino}phenyl)acetic acid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07423159B2
Source datasetuspto-grants-2008_09
ORD IDord-fd80a2d9bc6145b3915857d7ca3679ed
Source noteuspto-grants-2008_09