Diethyl Ether → 1,1-Dimethylethyl 4-hydroxy-4-(2-thiazolyl)-1-piperidinecarboxylate
Reaction equation
[Br:6][c:7]1[s:8][cH:9][cH:10][n:11]1.[C:12](=[O:13])([O:14][C:15]([CH3:16])([CH3:17])[CH3:18])[N:19]1[CH2:20][CH2:21][C:22](=[O:25])[CH2:23][CH2:24]1.[CH2:31]1[O:32][CH2:33][CH2:34][CH2:35]1.[CH3:1][CH2:2][CH2:3][CH2:4][Li:5].[CH3:26][CH2:27][O:28][CH2:29][CH3:30]>>[c:7]1([C:22]2([OH:25])[CH2:21][CH2:20][N:19]([C:12](=[O:13])[O:14][C:15]([CH3:16])([CH3:17])[CH3:18])[CH2:24][CH2:23]2)[s:8][cH:9][cH:10][n:11]1Participants
6
Sources & evidence
- ORD record
- ord-cd3ea65857b4487da94a3727cb8d366f
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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