Hydrochloric Acid → 2-[(1H-Pyrrolo[2,3-b]pyridin-4-ylmethyl)amino]-N-{3-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl}nicotinamide
Reaction equation
[ClH:27].[ClH:28].[F:1][c:2]1[c:3]([C:4](=[O:5])[NH:6][c:7]2[cH:8][c:9]([C:13]([C:14]([F:15])([F:16])[F:17])([C:18]([F:19])([F:20])[F:21])[OH:22])[cH:10][cH:11][cH:12]2)[cH:23][cH:24][cH:25][n:26]1.[nH:29]1[cH:30][cH:31][c:32]2[c:33]1[n:34][cH:35][cH:36][c:37]2[CH2:38][NH2:39]>>[c:2]1([NH:39][CH2:38][c:37]2[c:32]3[cH:31][cH:30][nH:29][c:33]3[n:34][cH:35][cH:36]2)[c:3]([C:4](=[O:5])[NH:6][c:7]2[cH:8][c:9]([C:13]([C:14]([F:15])([F:16])[F:17])([C:18]([F:19])([F:20])[F:21])[OH:22])[cH:10][cH:11][cH:12]2)[cH:23][cH:24][cH:25][n:26]1Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-edb65c9459d741aaaa39f41f74d3ac94
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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