Ethyl Acetate → tert-butyl 5-(3-(6-bromo-5-fluoropicolinamido)pyridin-4-yl)-2-oxohexahydrobenzo[d]oxazole-3(2H)-carboxylate
Reaction equation
[Br:25][c:26]1[c:27]([F:35])[cH:28][cH:29][c:30]([C:32](=[O:33])[OH:34])[n:31]1.[CH3:36][CH2:37][O:38][C:39]([CH3:40])=[O:41].[NH2:1][c:2]1[cH:3][n:4][cH:5][cH:6][c:7]1[CH:8]1[CH2:9][CH2:10][CH:11]2[CH:12]([N:13]([C:17](=[O:18])[O:19][C:20]([CH3:21])([CH3:22])[CH3:23])[C:14](=[O:16])[O:15]2)[CH2:24]1>>[NH:1]([c:2]1[cH:3][n:4][cH:5][cH:6][c:7]1[CH:8]1[CH2:9][CH2:10][CH:11]2[CH:12]([N:13]([C:17](=[O:18])[O:19][C:20]([CH3:21])([CH3:22])[CH3:23])[C:14](=[O:16])[O:15]2)[CH2:24]1)[C:32]([c:30]1[cH:29][cH:28][c:27]([F:35])[c:26]([Br:25])[n:31]1)=[O:33]Participants
4
Sources & evidence
- ORD record
- ord-b1fd8382aa8440fc968311b2ef96a975
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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