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HRID30807

反应详情

EQUATION

反应方程式

HRID 30807 的结构方程式

REACTANTS

反应物

2
结构：O=C(O)C(F)(F)F
HCID6422

未命名化合物

结构：CNc1cc(OC)c(Oc2ccnc(C(=O)OC(C)(C)C)c2)cc1[N+](=O)[O-]
HCID69003260

未命名化合物

PRODUCTS

生成物

1
结构：CNc1cc(OC)c(Oc2ccnc(C(=O)O)c2)cc1[N+](=O)[O-]
HCID69001904

未命名化合物

PROCEDURE

实验过程

Trifluoroacetic acid was added neat to tert-butyl 4-(2-methoxy-4-(methylamino)-5-nitrophenoxy)pyridine-2-carboxylate and stirred at room temperature for 5 hours. TFA was evaporated, solid product azeotroped with toluene then placed under vacuum for 24 hours to yield 4-(2-methoxy-4-(methylamino)-5-nitrophenoxy)pyridine-2-carboxylic acid. HPLC=3.07 min; MS: MH+=321

WORKUP

后处理

  1. customTFA was evaporated
  2. customsolid product azeotroped with toluene
  3. waitthen placed under vacuum for 24 hours