Dimethylformamide → 1H-Pyrazole, 1-[[(4S)-2,2-dimethyl-1,3-dioxolan-4-yl]methyl]-4-iodo-

HRID 308085Notes

Reaction equation

HRID 308085 reaction equation
[C:26](=[O:27])([O-:28])[O-:29].[CH3:7][c:8]1[cH:9][cH:10][c:11]([S:12]([O:13][CH2:18][CH:19]2[O:20][C:21]([CH3:24])([CH3:25])[O:22][CH2:23]2)(=[O:14])=[O:15])[cH:16][cH:17]1.[Cs+:30].[Cs+:31].[I:1][c:2]1[cH:3][n:4][nH:5][cH:6]1.[O:32]=[CH:33][N:34]([CH3:35])[CH3:36]>>[I:1][c:2]1[cH:3][n:4]([CH2:18][CH:19]2[O:20][C:21]([CH3:24])([CH3:25])[O:22][CH2:23]2)[n:5][cH:6]1

Participants

6

Reactant 5

HCID 6228DimethylformamideHCID 19660Carbonate IonHCID 770224-IodopyrazoleHCID 104967Cesium cation2×HCID 2350972,2-Dimethyl-1,3-dioxolan-4-ylmethyl p-toluenesulfonate

Product 1

HCID 771655421H-Pyrazole, 1-[[(4S)-2,2-dimethyl-1,3-dioxolan-4-yl]methyl]-4-iodo-

Sources & evidence

ORD record
ord-bd84a84605e24626b7f4024bd4c6ef2c
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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