Acetic Acid → 1-{4-Hydroxy-4-[5-(3-methyl-5-{[4-(trifluoromethyl)pyrimidin-2-yl]amino}phenyl)-1,3-thiazol-2-yl]piperidin-1-yl}ethanone
Reaction equation
[CH3:1][C:2]([OH:3])=[O:4].[CH3:45][N:46]([CH3:47])[CH:48]=[O:49].[CH3:5][c:6]1[cH:7][c:8](-[c:23]2[cH:24][n:25][c:26]([C:28]3([OH:34])[CH2:29][CH2:30][NH:31][CH2:32][CH2:33]3)[s:27]2)[cH:9][c:10]([NH:12][c:13]2[n:14][cH:15][cH:16][c:17]([C:19]([F:20])([F:21])[F:22])[n:18]2)[cH:11]1.[OH:35][c:36]1[c:37]2[n:38][n:39][nH:40][c:41]2[cH:42][cH:43][cH:44]1>>[CH3:1][C:2](=[O:3])[N:31]1[CH2:30][CH2:29][C:28]([c:26]2[n:25][cH:24][c:23](-[c:8]3[cH:7][c:6]([CH3:5])[cH:11][c:10]([NH:12][c:13]4[n:14][cH:15][cH:16][c:17]([C:19]([F:20])([F:21])[F:22])[n:18]4)[cH:9]3)[s:27]2)([OH:34])[CH2:33][CH2:32]1Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-fc16d304810c46acae2b286c15362340
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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