Thionyl Chloride → 4,4,4-trifluoro-N-[1-(4-fluorophenyl)-1-[3-fluoro-5-(1,1,2,2-tetrafluoroethoxy)phenyl]-2-phenylethyl]-2,2-dimethylbutanamide
Reaction equation
[F:16][c:17]1[cH:18][c:19]([C:30]([CH2:31][c:32]2[cH:33][cH:34][cH:35][cH:36][cH:37]2)([NH2:38])[c:39]2[cH:40][cH:41][c:42]([F:45])[cH:43][cH:44]2)[cH:20][c:21]([O:23][C:24]([CH:25]([F:26])[F:27])([F:28])[F:29])[cH:22]1.[F:1][C:2]([CH2:3][C:4]([C:5](=[O:6])[OH:7])([CH3:8])[CH3:9])([F:10])[F:11].[S:12]([Cl:13])([Cl:14])=[O:15]>>[F:1][C:2]([CH2:3][C:4]([C:5](=[O:6])[NH:38][C:30]([c:19]1[cH:18][c:17]([F:16])[cH:22][c:21]([O:23][C:24]([CH:25]([F:26])[F:27])([F:28])[F:29])[cH:20]1)([CH2:31][c:32]1[cH:33][cH:34][cH:35][cH:36][cH:37]1)[c:39]1[cH:40][cH:41][c:42]([F:45])[cH:43][cH:44]1)([CH3:8])[CH3:9])([F:10])[F:11]Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-06a3b9f53c5a4538aa2d7057c1711be6
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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