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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 308202Generated: October 25, 2026

Thionyl Chloride → 4,4,4-trifluoro-N-[1-(4-fluorophenyl)-1-[3-fluoro-5-(1,1,2,2-tetrafluoroethoxy)phenyl]-2-phenylethyl]-2,2-dimethylbutanamide

https://huagongshe.com/reaction/308202

Reaction equation

Participants

RoleNameHCIDCharge
ReactantThionyl ChlorideHCID 24386—
Reactant4,4,4-Trifluoro-2,2-dimethylbutanoic acidHCID 10057937—
Reactant1-(4-Fluorophenyl)-1-[3-fluoro-5-(1,1,2,2-tetrafluoroethoxy)phenyl]-2-phenylethanamineHCID 72290868—
Product4,4,4-trifluoro-N-[1-(4-fluorophenyl)-1-[3-fluoro-5-(1,1,2,2-tetrafluoroethoxy)phenyl]-2-phenylethyl]-2,2-dimethylbutanamideHCID 74065244—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (8/10)
ORD IDord-06a3b9f53c5a4538aa2d7057c1711be6
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (8/10)