Dichloromethane → tert-butyl 2-Oxa-5-azabicyclo[2.2.1]heptane-5-carboxylate

HRID 308294Notes

Reaction equation

HRID 308294 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH:9]([CH2:14][OH:15])[CH2:10][CH:11]([OH:13])[CH2:12]1.[Cl:49][CH2:50][Cl:51].[O:35]=[C:36]([O:37][CH:38]([CH3:39])[CH3:40])[N:41]=[N:42][C:43]([O:44][CH:45]([CH3:46])[CH3:47])=[O:48].[c:16]1([P:17]([c:18]2[cH:19][cH:20][cH:21][cH:22][cH:23]2)[c:24]2[cH:25][cH:26][cH:27][cH:28][cH:29]2)[cH:30][cH:31][cH:32][cH:33][cH:34]1>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH:9]2[CH2:10][CH:11]([CH2:12]1)[O:15][CH2:14]2

Participants

5

Reactant 4

HCID 6344DichloromethaneHCID 11776TriphenylphosphineHCID 75555Diisopropyl diazene-1,2-dicarboxylateHCID 4204845Tert-butyl 4-hydroxy-2-(hydroxymethyl)pyrrolidine-1-carboxylate

Product 1

HCID 14117043tert-butyl 2-Oxa-5-azabicyclo[2.2.1]heptane-5-carboxylate

Sources & evidence

ORD record
ord-eaf7810255e84af5b05717aa239883e5
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

Loading…