Water → 1-(3,4,5-Trimethoxybenzyl)-3-(4-fluorophenylmethyl)-2-oxopyrrolidine
Reaction equation
[CH3:1][O:2][c:3]1[cH:4][c:5]([CH2:6][N:7]2[C:8](=[O:12])[CH2:9][CH2:10][CH2:11]2)[cH:13][c:14]([O:18][CH3:19])[c:15]1[O:16][CH3:17].[CH:25]([Li:26])([CH2:27][CH3:28])[CH3:29].[F:30][c:31]1[cH:32][cH:33][c:34]([CH2:35][Br:36])[cH:37][cH:38]1.[O:20]1[CH2:21][CH2:22][CH2:23][CH2:24]1.[OH2:39]>>[CH3:1][O:2][c:3]1[cH:4][c:5]([CH2:6][N:7]2[C:8](=[O:12])[CH:9]([CH2:35][c:34]3[cH:33][cH:32][c:31]([F:30])[cH:38][cH:37]3)[CH2:10][CH2:11]2)[cH:13][c:14]([O:18][CH3:19])[c:15]1[O:16][CH3:17]Participants
6
Sources & evidence
- ORD record
- ord-332b2feb28fb451781a8992042e67120
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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