Diethyl Ether → 7a-(5-Bromo-2-fluorophenyl)-1,3,3a,4,5,7-hexahydropyrano[3,4-c][1,2]oxazole
Reaction equation
[B:29]([F:30])([F:31])[F:32].[Br:1][c:2]1[cH:3][c:4]([Br:9])[c:5]([F:8])[cH:6][cH:7]1.[CH2:10]([Li:11])[CH2:12][CH2:13][CH3:14].[CH2:24]([O:25][CH2:26][CH3:27])[CH3:28].[N:15]1=[C:19]2[CH:18]([CH2:17][O:16]1)[CH2:23][CH2:22][O:21][CH2:20]2>>[Br:1][c:2]1[cH:3][c:4]([C:19]23[NH:15][O:16][CH2:17][CH:18]2[CH2:23][CH2:22][O:21][CH2:20]3)[c:5]([F:8])[cH:6][cH:7]1Participants
6
Sources & evidence
- ORD record
- ord-71575722baa7476fb1a13ab062d1d541
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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