1-Butanol → 2,6-Dichloropyrimidin-4-yl-(5-isopropyl-1H-pyrazol-3-yl)-amine

HRID 308779Notes

Reaction equation

HRID 308779 reaction equation
[CH2:28]([OH:29])[CH2:30][CH2:31][CH3:32].[CH:10]([CH3:11])([CH3:12])[c:13]1[cH:14][c:15]([NH2:18])[n:16][nH:17]1.[CH:19]([N:20]([CH:21]([CH3:22])[CH3:23])[CH2:24][CH3:25])([CH3:26])[CH3:27].[Cl:1][c:2]1[n:3][c:4]([Cl:9])[cH:5][c:6]([Cl:8])[n:7]1>>[Cl:1][c:2]1[n:3][c:4]([NH:18][c:15]2[cH:14][c:13]([CH:10]([CH3:11])[CH3:12])[nH:17][n:16]2)[cH:5][c:6]([Cl:8])[n:7]1

Participants

5

Reactant 4

HCID 2631-ButanolHCID 773782,4,6-TrichloropyrimidineHCID 81531DiisopropylethylamineHCID 27695273-(propan-2-yl)-1H-pyrazol-5-amine

Product 1

HCID 578664512,6-Dichloropyrimidin-4-yl-(5-isopropyl-1H-pyrazol-3-yl)-amine

Sources & evidence

ORD record
ord-5b19bb9dc77f4626bf469c7f95372a0e
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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