Dichloromethane → 2,2-Dimethylpropionic acid 3-[2-(4-chlorophenyl)-5-ethylthiazol-4-yl]-4-oxobicyclo[3.2.1]oct-2-en-2-yl ester

HRID 308847Notes

Reaction equation

HRID 308847 reaction equation
[C:32]([C:33]([CH3:34])([CH3:35])[CH3:36])(=[O:37])[Cl:38].[CH3:25][CH2:26][N:27]([CH2:28][CH3:29])[CH2:30][CH3:31].[Cl:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[s:9][c:10]([CH2:23][CH3:24])[c:11]([CH:13]3[C:14](=[O:22])[CH:15]4[CH2:16][CH2:17][CH:18]([C:19]3=[O:20])[CH2:21]4)[n:12]2)[cH:6][cH:7]1.[Cl:39][CH2:40][Cl:41]>>[Cl:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[s:9][c:10]([CH2:23][CH3:24])[c:11]([C:13]3=[C:19]([O:20][C:32]([C:33]([CH3:34])([CH3:35])[CH3:36])=[O:37])[CH:18]4[CH2:17][CH2:16][CH:15]([C:14]3=[O:22])[CH2:21]4)[n:12]2)[cH:6][cH:7]1

Participants

5

Reactant 4

HCID 6344DichloromethaneHCID 8471TriethylamineHCID 62493Pivaloyl chlorideHCID 667420403-[2-(4-Chlorophenyl)-5-ethylthiazol-4-yl]bicyclo[3.2.1]octane-2,4-dione

Product 1

HCID 667425252,2-Dimethylpropionic acid 3-[2-(4-chlorophenyl)-5-ethylthiazol-4-yl]-4-oxobicyclo[3.2.1]oct-2-en-2-yl ester

Sources & evidence

ORD record
ord-099e1474a1d744da98c8b634b9787afe
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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