Methanol → 2-((cyclopropylamino)(4-fluorophenyl)methyl)-N-(5-methyl-1H-pyrazol-3-yl)quinazolin-4-amine
Reaction equation
[BH4-:31].[CH3:33][OH:34].[CH3:35][CH:36]([OH:37])[CH3:38].[CH:27]1([NH2:30])[CH2:28][CH2:29]1.[F:1][c:2]1[cH:3][cH:4][c:5]([C:8](=[O:9])[c:10]2[n:11][c:12]3[cH:13][cH:14][cH:15][cH:16][c:17]3[c:18]([NH:20][c:21]3[n:22][nH:23][c:24]([CH3:26])[cH:25]3)[n:19]2)[cH:6][cH:7]1.[Na+:32]>>[F:1][c:2]1[cH:3][cH:4][c:5]([CH:8]([c:10]2[n:11][c:12]3[cH:13][cH:14][cH:15][cH:16][c:17]3[c:18]([NH:20][c:21]3[n:22][nH:23][c:24]([CH3:26])[cH:25]3)[n:19]2)[NH:30][CH:27]2[CH2:28][CH2:29]2)[cH:6][cH:7]1Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-4682e165dc5341e2b7fa603cbca294bd
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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