Methanol → 1-(4-fluoro-phenyl)-5-hydroxymethyl-4-isopropyl-1H-pyrazole-3-carboxylic acid benzylamide
Reaction equation
[BH4-:30].[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[NH:8][C:9](=[O:10])[c:11]1[n:12][n:13](-[c:21]2[cH:22][cH:23][c:24]([F:27])[cH:25][cH:26]2)[c:14]([CH:19]=[O:20])[c:15]1[CH:16]([CH3:17])[CH3:18].[CH2:32]1[O:33][CH2:34][CH2:35][CH2:36]1.[CH3:28][OH:29].[Na+:31]>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[NH:8][C:9](=[O:10])[c:11]1[n:12][n:13](-[c:21]2[cH:22][cH:23][c:24]([F:27])[cH:25][cH:26]2)[c:14]([CH2:19][OH:20])[c:15]1[CH:16]([CH3:17])[CH3:18]Participants
6
Sources & evidence
- ORD record
- ord-cd3958f0651244e1a51f5597f9343b45
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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