Tetrahydrofuran → methyl 3-(1-(4-fluorophenyl)-1H-indazol-5-yl)-2-(hydroxymethyl)-2-methyl-3-phenylpropanoate

HRID 309359Notes

Reaction equation

HRID 309359 reaction equation
[CH2:34]1[O:35][CH2:36][CH2:37][CH2:38]1.[F:1][c:2]1[cH:3][cH:4][c:5](-[n:8]2[n:9][cH:10][c:11]3[cH:12][c:13]([CH:17]([C:18]([C:19](=[O:20])[O:21][CH3:22])([C:23](=[O:24])[O:25][CH3:26])[CH3:27])[c:28]4[cH:29][cH:30][cH:31][cH:32][cH:33]4)[cH:14][cH:15][c:16]23)[cH:6][cH:7]1>>[F:1][c:2]1[cH:3][cH:4][c:5](-[n:8]2[n:9][cH:10][c:11]3[cH:12][c:13]([CH:17]([C:18]([C:19](=[O:20])[O:21][CH3:22])([CH2:23][OH:24])[CH3:27])[c:28]4[cH:29][cH:30][cH:31][cH:32][cH:33]4)[cH:14][cH:15][c:16]23)[cH:6][cH:7]1

Participants

3

Reactant 2

HCID 8028TetrahydrofuranHCID 67005816dimethyl 2-((1-(4-fluorophenyl)-1H-indazol-5-yl)(phenyl)methyl)-2-methylmalonate

Product 1

HCID 59252864methyl 3-(1-(4-fluorophenyl)-1H-indazol-5-yl)-2-(hydroxymethyl)-2-methyl-3-phenylpropanoate

Sources & evidence

ORD record
ord-545418ab74ab43e3b0be39d81bac2725
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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