Toluene → 4-(azetidin-1-yl)-5-[5-(5-chloro-3-fluoropyridin-2-yl)-1-methyl-1H-pyrazol-4-yl]-7-methylimidazo[5,1-f][1,2,4]triazine
Reaction equation
[CH3:34][c:35]1[cH:36][cH:37][cH:38][cH:39][cH:40]1.[Cl:22][c:23]1[cH:24][c:25]([F:33])[c:26]([Sn:29]([CH3:30])([CH3:31])[CH3:32])[n:27][cH:28]1.[N:1]1([c:5]2[n:6][cH:7][n:8][n:9]3[c:10]2[c:11](-[c:15]2[cH:16][n:17][n:18]([CH3:21])[c:19]2[Br:20])[n:12][c:13]3[CH3:14])[CH2:2][CH2:3][CH2:4]1.[Pd:41]([Cl:42])[Cl:43].[c:44]1([P:45]([c:46]2[cH:47][cH:48][cH:49][cH:50][cH:51]2)[c:52]2[cH:53][cH:54][cH:55][cH:56][cH:57]2)[cH:58][cH:59][cH:60][cH:61][cH:62]1.[c:63]1([P:64]([c:65]2[cH:66][cH:67][cH:68][cH:69][cH:70]2)[c:71]2[cH:72][cH:73][cH:74][cH:75][cH:76]2)[cH:77][cH:78][cH:79][cH:80][cH:81]1>>[N:1]1([c:5]2[n:6][cH:7][n:8][n:9]3[c:10]2[c:11](-[c:15]2[cH:16][n:17][n:18]([CH3:21])[c:19]2-[c:26]2[c:25]([F:33])[cH:24][c:23]([Cl:22])[cH:28][n:27]2)[n:12][c:13]3[CH3:14])[CH2:2][CH2:3][CH2:4]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-0e7a3464ef6a444e9710ac5a6a5cdbd9
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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