Diisopropylethylamine → 5-Chloro-3-(4-chloro-3-trifluoromethyl-benzenesulfonylamino)-pyridine-2-carboxylic acid (2,4-difluoro-phenyl)-methyl-amide

HRID 309521Notes

Reaction equation

HRID 309521 reaction equation
[CH:36]([N:37]([CH2:38][CH3:39])[CH:40]([CH3:41])[CH3:42])([CH3:43])[CH3:44].[Cl:1][c:2]1[cH:3][c:4]([NH:11][S:12](=[O:13])(=[O:14])[c:15]2[cH:16][c:17]([C:22]([F:23])([F:24])[F:25])[c:18]([Cl:21])[cH:19][cH:20]2)[c:5]([C:8](=[O:9])[OH:10])[n:6][cH:7]1.[F:26][c:27]1[c:28]([NH:34][CH3:35])[cH:29][cH:30][c:31]([F:33])[cH:32]1>>[Cl:1][c:2]1[cH:3][c:4]([NH:11][S:12](=[O:13])(=[O:14])[c:15]2[cH:16][c:17]([C:22]([F:23])([F:24])[F:25])[c:18]([Cl:21])[cH:19][cH:20]2)[c:5]([C:8](=[O:10])[N:34]([c:28]2[c:27]([F:26])[cH:32][c:31]([F:33])[cH:30][cH:29]2)[CH3:35])[n:6][cH:7]1

Participants

4

Reactant 3

HCID 81531DiisopropylethylamineHCID 27370232,4-difluoro-N-methylanilineHCID 579420775-Chloro-3-(4-chloro-3-trifluoromethyl benzenesulfonylamino)-pyridine-2-carboxylic acid

Product 1

HCID 579421515-Chloro-3-(4-chloro-3-trifluoromethyl-benzenesulfonylamino)-pyridine-2-carboxylic acid (2,4-difluoro-phenyl)-methyl-amide

Sources & evidence

ORD record
ord-8c0b2154e349454e86e4bc993b5e3e4b
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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