Tetrahydrofuran → 5-{4-[2-(tert-Butyl-dimethyl-silanyloxy)-ethoxy]-benzoyl}-2-chloro-benzenesulfonamide
Reaction equation
[Br:1][c:2]1[cH:3][cH:4][c:5]([O:6][CH2:7][CH2:8][O:9][Si:10]([CH3:11])([CH3:12])[C:13]([CH3:14])([CH3:15])[CH3:16])[cH:17][cH:18]1.[CH2:19]([Li:20])[CH2:21][CH2:22][CH3:23].[Cl:24][c:25]1[c:26]([S:37]([NH2:38])(=[O:39])=[O:40])[cH:27][c:28]([C:29](=[O:30])[N:31]([O:32][CH3:33])[CH3:34])[cH:35][cH:36]1.[O:41]1[CH2:42][CH2:43][CH2:44][CH2:45]1>>[c:2]1([C:29]([c:28]2[cH:27][c:26]([S:37]([NH2:38])(=[O:39])=[O:40])[c:25]([Cl:24])[cH:36][cH:35]2)=[O:30])[cH:3][cH:4][c:5]([O:6][CH2:7][CH2:8][O:9][Si:10]([CH3:11])([CH3:12])[C:13]([CH3:14])([CH3:15])[CH3:16])[cH:17][cH:18]1Participants
5
Sources & evidence
- ORD record
- ord-46aaf7a09c784c54b72c28e03cf38c88
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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