Dichloromethane → N,N-Dimethyl-5-[(2-methyl-6-{[(5-methylpyridin-2-yl)amino]-carbonyl}-1-benzofuran-4-yl)oxy]pyridine-2-carboxamide

HRID 310135Notes

Reaction equation

HRID 310135 reaction equation
[CH3:1][c:2]1[cH:3][cH:4][c:5]([NH2:8])[n:6][cH:7]1.[CH3:9][N:10]([C:11](=[O:12])[c:13]1[cH:14][cH:15][c:16]([O:19][c:20]2[cH:21][c:22]([C:30](=[O:31])[O:32][CH2:33][CH3:34])[cH:23][c:24]3[c:25]2[cH:26][c:27]([CH3:29])[o:28]3)[cH:17][n:18]1)[CH3:35].[Cl:36][CH2:37][Cl:38]>>[CH3:1][c:2]1[cH:3][cH:4][c:5]([NH:8][C:30]([c:22]2[cH:21][c:20]([O:19][c:16]3[cH:15][cH:14][c:13]([C:11]([N:10]([CH3:9])[CH3:35])=[O:12])[n:18][cH:17]3)[c:25]3[c:24]([cH:23]2)[o:28][c:27]([CH3:29])[cH:26]3)=[O:31])[n:6][cH:7]1

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 153482-Amino-5-methylpyridineHCID 59559976Ethyl 4-({6-[(dimethylamino)carbonyl]pyridin-3-yl}oxy)-2-methyl-1-benzofuran-6-carboxylate

Product 1

HCID 59560431N,N-Dimethyl-5-[(2-methyl-6-{[(5-methylpyridin-2-yl)amino]-carbonyl}-1-benzofuran-4-yl)oxy]pyridine-2-carboxamide

Sources & evidence

ORD record
ord-e26e2bcd6ee542f6ac62b01491279504
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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