Hydrochloric Acid → cis-1-{4-[(5-Chloro-indan-2-ylmethyl)-amino]-cyclohexyl}-2-methyl-1H-benzoimidazole-5-carbonitrile

HRID 310137Notes

Reaction equation

HRID 310137 reaction equation
[Cl:21][c:22]1[cH:23][c:24]2[c:28]([cH:29][cH:30]1)[CH2:27][CH:26]([CH:31]=[O:32])[CH2:25]2.[ClH:1].[NH2:2][CH:3]1[CH2:4][CH2:5][CH:6]([n:9]2[c:10]([CH3:20])[n:11][c:12]3[c:13]2[cH:14][cH:15][c:16]([C:18]#[N:19])[cH:17]3)[CH2:7][CH2:8]1>>[NH:2]([CH:3]1[CH2:4][CH2:5][CH:6]([n:9]2[c:10]([CH3:20])[n:11][c:12]3[c:13]2[cH:14][cH:15][c:16]([C:18]#[N:19])[cH:17]3)[CH2:7][CH2:8]1)[CH2:31][CH:26]1[CH2:25][c:24]2[cH:23][c:22]([Cl:21])[cH:30][cH:29][c:28]2[CH2:27]1

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 59135483cis-1-(4-amino-cyclohexyl)-2-methyl-1H-benzoimidazole-5-carbonitrileHCID 86620957HCID 86620957, compound

Product 1

HCID 59135492cis-1-{4-[(5-Chloro-indan-2-ylmethyl)-amino]-cyclohexyl}-2-methyl-1H-benzoimidazole-5-carbonitrile

Sources & evidence

ORD record
ord-eb053c9221644c8eac6fa68a9ed3e0b4
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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