Acetone → 2-Benzyl-3-[4-(benzyloxy)phenyl]-7-(trifluoromethyl)-2H-indazole

HRID 310188Notes

Reaction equation

HRID 310188 reaction equation
[C:36](=[O:37])([O-:38])[O-:39].[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[n:8]1[n:9][c:10]2[c:11]([C:24]([F:25])([F:26])[F:27])[cH:12][cH:13][cH:14][c:15]2[c:16]1-[c:17]1[cH:18][cH:19][c:20]([OH:23])[cH:21][cH:22]1.[CH2:28]([c:29]1[cH:30][cH:31][cH:32][cH:33][cH:34]1)[Br:35].[CH3:42][C:43](=[O:44])[CH3:45].[K+:40].[K+:41]>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[n:8]1[n:9][c:10]2[c:11]([C:24]([F:25])([F:26])[F:27])[cH:12][cH:13][cH:14][c:15]2[c:16]1-[c:17]1[cH:18][cH:19][c:20]([O:23][CH2:28][c:29]2[cH:30][cH:31][cH:32][cH:33][cH:34]2)[cH:21][cH:22]1

Participants

6

Reactant 5

HCID 180AcetoneHCID 813Potassium Cation2×HCID 7498Benzyl BromideHCID 19660Carbonate IonHCID 136393280HCID 136393280, compound

Product 1

HCID 688185992-Benzyl-3-[4-(benzyloxy)phenyl]-7-(trifluoromethyl)-2H-indazole

Sources & evidence

ORD record
ord-68c9fcf9187b444da330694aab143b53
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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