Dichloromethane → 4-[3-(2-Methyl-pyridin-3-yl)-phenyl]-8-trifluoromethyl-1,3-dihydro-benzo[b][1,4]diazepin-2-one
Reaction equation
[C:1]([O:2][C:3](=[O:4])[NH:7][c:8]1[c:9]([NH:18][C:19]([CH2:20][C:21](=[O:5])[c:23]2[cH:24][c:25](-[c:29]3[c:30]([CH3:35])[n:31][cH:32][cH:33][cH:34]3)[cH:26][cH:27][cH:28]2)=[O:36])[cH:10][c:11]([C:14]([F:15])([F:16])[F:17])[cH:12][cH:13]1)([CH3:6])([CH3:22])[CH3:37].[Cl:45][CH2:46][Cl:47].[F:38][C:39]([F:40])([F:41])[C:42]([OH:43])=[O:44]>>[N:7]1=[C:21]([c:23]2[cH:24][c:25](-[c:29]3[c:30]([CH3:35])[n:31][cH:32][cH:33][cH:34]3)[cH:26][cH:27][cH:28]2)[CH2:20][C:19](=[O:36])[NH:18][c:9]2[c:8]1[cH:13][cH:12][c:11]([C:14]([F:15])([F:16])[F:17])[cH:10]2Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-c3e2e4f95ae14daeb27b0af657691068
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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