Tetrahydrofuran → HCID 66997644, compound

HRID 310311Notes

Reaction equation

[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][CH2:9][CH2:10][N:11]([C:12](=[O:13])[c:14]1[nH:15][c:16](=[O:36])[c:17]([O:34][CH3:35])[c:18]2[c:23]1[CH2:22][CH2:21][N:20]([CH2:24][c:25]1[cH:26][c:27]([Cl:32])[c:28]([F:31])[cH:29][cH:30]1)[C:19]2=[O:33])[CH2:37][CH2:38][CH2:39][CH2:40][O:41][Si:42]([C:43]([CH3:44])([CH3:45])[CH3:46])([CH3:47])[CH3:48].[CH2:50]([N+:51]([CH2:52][CH2:53][CH2:54][CH3:55])([CH2:56][CH2:57][CH2:58][CH3:59])[CH2:60][CH2:61][CH2:62][CH3:63])[CH2:64][CH2:65][CH3:66].[CH2:67]1[O:68][CH2:69][CH2:70][CH2:71]1.[F-:49]>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][CH2:9][CH2:10][N:11]([C:12](=[O:13])[c:14]1[nH:15][c:16](=[O:36])[c:17]([O:34][CH3:35])[c:18]2[c:23]1[CH2:22][CH2:21][N:20]([CH2:24][c:25]1[cH:26][c:27]([Cl:32])[c:28]([F:31])[cH:29][cH:30]1)[C:19]2=[O:33])[CH2:37][CH2:38][CH2:39][CH2:40][OH:41]

Participants

Reactant 4

HCID 8028Tetrahydrofuran

HCID 16028Tetrabutylammonium

HCID 28179Fluoride Ion

HCID 66996905N-[2-(Benzyloxy)ethyl]-N-(4-{[tert-butyl(dimethyl)silyl]oxy}butyl)-6-(3-chloro-4-fluorobenzyl)-4-methoxy-3,5-dioxo-2,3,5,6,7,8-hexahydro-2,6-naphthyridine-1-carboxamide

Product 1

HCID 66997644HCID 66997644, compound

Sources & evidence

ORD record: ord-c6015b825bdd46ab94af4eb3f35710fd
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (8/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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