Hydrochloric Acid → 1-(4'-(6-Carbamoyl-3,5-dimethylpyrazin-2-yl)-2-chlorobiphenyl-4-yl)cyclopropanecarboxylic acid
Reaction equation
[C:3]([NH2:4])(=[O:5])[c:6]1[c:7]([CH3:33])[n:8][c:9]([CH3:32])[c:10](-[c:12]2[cH:13][cH:14][c:15](-[c:18]3[c:19]([Cl:31])[cH:20][c:21]([C:24]4([C:27](=[O:28])[O:29][CH3:30])[CH2:25][CH2:26]4)[cH:22][cH:23]3)[cH:16][cH:17]2)[n:11]1.[CH3:35][C:36]([OH:37])([CH3:38])[CH3:39].[ClH:34].[K+:2].[OH-:1]>>[C:3]([NH2:4])(=[O:5])[c:6]1[c:7]([CH3:33])[n:8][c:9]([CH3:32])[c:10](-[c:12]2[cH:13][cH:14][c:15](-[c:18]3[c:19]([Cl:31])[cH:20][c:21]([C:24]4([C:27](=[O:28])[OH:29])[CH2:25][CH2:26]4)[cH:22][cH:23]3)[cH:16][cH:17]2)[n:11]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-184b5fc3d20d4e359ceb4775d0a32bb2
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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