HCID 86601065, compound → HCID 86601064, compound

HRID 31072Notes

Reaction equation

HRID 31072 reaction equation
[NH2:1][C:2]1[N:7]([CH2:8][C:9]2[CH:14]=[CH:13][C:12]([O:15][CH3:16])=[CH:11][CH:10]=2)[C:6](=[S:17])[NH:5][C:4](=[O:18])[C:3]=1[N:19]=O>C(O)(=O)C>[NH2:19][C:3]1[C:4](=[O:18])[NH:5][C:6](=[S:17])[N:7]([CH2:8][C:9]2[CH:10]=[CH:11][C:12]([O:15][CH3:16])=[CH:13][CH:14]=2)[C:2]=1[NH2:1]

Participants

3

Reactant 1

HCID 86601065HCID 86601065, compound

Product 1

HCID 86601064HCID 86601064, compoundYield 73%

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

The title compound was prepared according to the general method of Example 14 (c) except that dilute acetic acid was used for neutralization of the reaction mixture. The desired product (0.83 g, 73%) was prepared as a yellow solid starting from 6-amino-1-(4-methoxybenzyl)-5-nitroso-2-thioxo-2,3-dihydro-1H-pyrimidin-4-one (1.2 g, 4.1 mmol).

Workup

  1. customThe title compound was prepared

Sources & evidence

ORD record
ord-cbc0049e41334b26aa1b0f09e69672b6
Source dataset
uspto-grants-2008_09
Patent number
US07425560B2

Reaction notes

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