2-(Dimethylamino)ethanol → (6-Chloro-3-cyclopropylpyridin-2-yl)(2-fluoropyridin-3-yl)methanone
Reaction equation
[CH3:1][CH2:2][CH2:3][CH2:4][Li:5].[CH3:35][CH2:36][CH2:37][CH2:38][CH2:39][CH3:40].[CH3:6][N:7]([CH2:8][CH2:9][OH:10])[CH3:11].[Cl:12][c:13]1[n:14][cH:15][c:16]([CH:19]2[CH2:20][CH2:21]2)[cH:17][cH:18]1.[F:22][c:23]1[c:24]([C:25](=[O:26])[N:27]([O:28][CH3:29])[CH3:30])[cH:31][cH:32][cH:33][n:34]1.[O:41]1[CH2:42][CH2:43][CH2:44][CH2:45]1>>[Cl:12][c:13]1[n:14][c:15]([C:25]([c:24]2[c:23]([F:22])[n:34][cH:33][cH:32][cH:31]2)=[O:26])[c:16]([CH:19]2[CH2:20][CH2:21]2)[cH:17][cH:18]1Participants
7
Sources & evidence
- ORD record
- ord-dc514b6590104954947048ee75f090d1
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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