Pyridine → N-[6-chloro-4-(2,2,2-trifluoro-acetylamino)-9H-beta-carbolin-8-yl]-2-methyl-nicotinamide
Reaction equation
[CH3:23][c:24]1[c:25]([C:26](=[O:27])[OH:28])[cH:29][cH:30][cH:31][n:32]1.[CH3:33][CH2:34][N:35]=[C:36]=[N:37][CH2:38][CH2:39][CH2:40][N:41]([CH3:42])[CH3:43].[NH2:1][c:2]1[cH:3][c:4]([Cl:22])[cH:5][c:6]2[c:7]3[c:8]([NH:15][C:16]([C:17]([F:18])([F:19])[F:20])=[O:21])[cH:9][n:10][cH:11][c:12]3[nH:13][c:14]12.[cH:44]1[cH:45][cH:46][n:47][cH:48][cH:49]1>>[NH:1]([c:2]1[cH:3][c:4]([Cl:22])[cH:5][c:6]2[c:7]3[c:8]([NH:15][C:16]([C:17]([F:18])([F:19])[F:20])=[O:21])[cH:9][n:10][cH:11][c:12]3[nH:13][c:14]12)[C:26]([c:25]1[c:24]([CH3:23])[n:32][cH:31][cH:30][cH:29]1)=[O:27]Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-5994fc2b647e48c0b1cf112da680b438
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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