Tetrahydrofuran → 4-Fluoro-2-hydroxymethyl-pyrrolidine-1-carboxylic acid tert-butyl ester
Reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH:9]([C:14](=[O:15])[OH:16])[CH2:10][CH:11]([F:13])[CH2:12]1.[CH2:17]1[O:18][CH2:19][CH2:20][CH2:21]1>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH:9]([CH2:14][OH:15])[CH2:10][CH:11]([F:13])[CH2:12]1Participants
3
Sources & evidence
- ORD record
- ord-9334cd78dfcd45428df0eeb733d6bb72
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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