Acetic Acid → Methyl 4-((tert-butoxycarbonyl)amino)nicotinate

HRID 311187Notes

Reaction equation

HRID 311187 reaction equation
[C:1](=[O:2])([O:3][C:4]([CH3:5])([CH3:6])[CH3:7])[NH:8][c:9]1[c:10]([C:15](=[O:16])[OH:17])[cH:11][n:12][cH:13][cH:14]1.[CH3:18][Si:19]([CH:20]=[N+:21]=[N-:22])([CH3:23])[CH3:24].[CH3:25][C:26](=[O:27])[OH:28].[CH3:29][OH:30]>>[C:1](=[O:2])([O:3][C:4]([CH3:5])([CH3:6])[CH3:7])[NH:8][c:9]1[c:10]([C:15](=[O:16])[O:17][CH3:18])[cH:11][n:12][cH:13][cH:14]1

Participants

5

Reactant 4

HCID 176Acetic AcidHCID 887MethanolHCID 167693TrimethylsilyldiazomethaneHCID 221726234-{[(Tert-butoxy)carbonyl]amino}pyridine-3-carboxylic acid

Product 1

HCID 23438729Methyl 4-((tert-butoxycarbonyl)amino)nicotinate

Sources & evidence

ORD record
ord-1cf27f8f2d494a09a2c61e2044c07902
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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