Chloroacetyl chloride → 2-chloro-N-(isoquinolin-6-yl)acetamide
Reaction equation
[CH2:25]1[O:26][CH2:27][CH2:28][CH2:29]1.[CH:12]([NH:13][CH:14]([CH3:15])[CH3:16])([CH3:17])[CH3:18].[Cl:20][CH2:21][C:22](=[O:23])[Cl:24].[Li:19].[NH2:1][c:2]1[cH:3][c:4]2[cH:5][cH:6][n:7][cH:8][c:9]2[cH:10][cH:11]1>>[NH:1]([c:2]1[cH:3][c:4]2[cH:5][cH:6][n:7][cH:8][c:9]2[cH:10][cH:11]1)[C:22]([CH2:21][Cl:20])=[O:23]Participants
6
Sources & evidence
- ORD record
- ord-191395aab2a04a1bbf3b73954fb1dd2a
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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