Dichloromethane → 1-(4-{4-[2-(Benzyloxy)-1,1,1,3,3,3-hexafluoropropan-2-yl]-2-(prop-1-en-1-yl)phenyl}piperazin-1-yl)-2-bromoethanone

HRID 311640Notes

Reaction equation

HRID 311640 reaction equation
[Br:33][CH2:34][C:35](=[O:36])[Br:37].[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][C:9]([C:10]([F:11])([F:12])[F:13])([C:14]([F:15])([F:16])[F:17])[c:18]1[cH:19][c:20]([CH:30]=[CH:31][CH3:32])[c:21]([N:24]2[CH2:25][CH2:26][NH:27][CH2:28][CH2:29]2)[cH:22][cH:23]1.[Cl:38][CH2:39][Cl:40]>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][C:9]([C:10]([F:11])([F:12])[F:13])([C:14]([F:15])([F:16])[F:17])[c:18]1[cH:19][c:20]([CH:30]=[CH:31][CH3:32])[c:21]([N:24]2[CH2:25][CH2:26][N:27]([C:35]([CH2:34][Br:33])=[O:36])[CH2:28][CH2:29]2)[cH:22][cH:23]1

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 61147Bromoacetyl bromideHCID 91127540HCID 91127540, compound

Product 1

HCID 866471931-(4-{4-[2-(Benzyloxy)-1,1,1,3,3,3-hexafluoropropan-2-yl]-2-(prop-1-en-1-yl)phenyl}piperazin-1-yl)-2-bromoethanone

Sources & evidence

ORD record
ord-baf4f1cb27974ae697a31d5a1a048344
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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