N-methyl-2-pyrrolidone → 5-[[5-(4-hydroxy-2-methyloxan-4-yl)-1,3-thiazol-2-yl]sulfanyl]-1-methyl-3H-indol-2-one

HRID 311810Notes

Reaction equation

HRID 311810 reaction equation
[CH3:27][N:28]1[CH2:29][CH2:30][CH2:31][C:32]1=[O:33].[Cl:13][c:14]1[s:15][c:16]([C:19]2([OH:26])[CH2:20][CH:21]([CH3:25])[O:22][CH2:23][CH2:24]2)[cH:17][n:18]1.[SH:1][c:2]1[cH:3][c:4]2[c:8]([cH:9][cH:10]1)[N:7]([CH3:11])[C:6](=[O:12])[CH2:5]2>>[S:1]([c:2]1[cH:3][c:4]2[c:8]([cH:9][cH:10]1)[N:7]([CH3:11])[C:6](=[O:12])[CH2:5]2)[c:14]1[s:15][c:16]([C:19]2([OH:26])[CH2:20][CH:21]([CH3:25])[O:22][CH2:23][CH2:24]2)[cH:17][n:18]1

Participants

4

Reactant 3

HCID 13387N-methyl-2-pyrrolidoneHCID 224137484-(2-Chloro-1,3-thiazol-5-yl)-2-methyloxan-4-olHCID 224137491-methyl-5-sulfanyl-2,3-dihydro-1H-indol-2-one

Product 1

HCID 189987385-[[5-(4-hydroxy-2-methyloxan-4-yl)-1,3-thiazol-2-yl]sulfanyl]-1-methyl-3H-indol-2-one

Sources & evidence

ORD record
ord-94b242271c6444189d6cd91da8b7480c
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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