Methanol → N-Methyl-4-(5,6,7,8-tetrahydropyrazolo[3,4-d]azepin-2(4H)-yl)benzamide

HRID 311907Notes

Reaction equation

HRID 311907 reaction equation
[CH3:1][NH:2][C:3](=[O:4])[c:5]1[cH:6][cH:7][c:8](-[n:11]2[n:12][c:13]3[c:19]([cH:20]2)[CH2:18][CH2:17][N:16]([C:21]([O:22][C:23]([CH3:24])([CH3:25])[CH3:26])=[O:27])[CH2:15][CH2:14]3)[cH:9][cH:10]1.[CH3:38][OH:39].[Cl:35][CH2:36][Cl:37].[OH:28][C:29]([C:30]([F:31])([F:32])[F:33])=[O:34]>>[CH3:1][NH:2][C:3](=[O:4])[c:5]1[cH:6][cH:7][c:8](-[n:11]2[n:12][c:13]3[c:19]([cH:20]2)[CH2:18][CH2:17][NH:16][CH2:15][CH2:14]3)[cH:9][cH:10]1

Participants

5

Reactant 4

HCID 887MethanolHCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 669307901,1-Dimethylethyl 2-{4-[(methylamino)carbonyl]phenyl}-4,5,7,8-tetrahydropyrazolo[3,4-d]azepine-6(2H)-carboxylate

Product 1

HCID 66930754N-Methyl-4-(5,6,7,8-tetrahydropyrazolo[3,4-d]azepin-2(4H)-yl)benzamide

Sources & evidence

ORD record
ord-cc7d205a104a41119c5858ed847fbb22
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

Loading…