Methanol → 2-amino-5-[4-(difluoromethoxy)phenyl]-5-(3-{[(2-furylmethyl)-amino]methyl}phenyl)-3-methyl-3,5-dihydro-4H-imidazol-4-one

HRID 312123Notes

Reaction equation

HRID 312123 reaction equation
[BH4-:34].[CH2:27]([c:28]1[cH:29][cH:30][cH:31][o:32]1)[NH2:33].[CH3:38][OH:39].[NH2:1][C:2]1=[N:6][C:5]([c:7]2[cH:8][cH:9][c:10]([O:13][CH:14]([F:15])[F:16])[cH:11][cH:12]2)([c:17]2[cH:18][c:19]([CH:20]=[O:21])[cH:22][cH:23][cH:24]2)[C:4](=[O:25])[N:3]1[CH3:26].[Na+:35].[Na+:37].[OH-:36]>>[NH2:1][C:2]1=[N:6][C:5]([c:7]2[cH:8][cH:9][c:10]([O:13][CH:14]([F:15])[F:16])[cH:11][cH:12]2)([c:17]2[cH:18][c:19]([CH2:20][NH:33][CH2:27][c:28]3[cH:29][cH:30][cH:31][o:32]3)[cH:22][cH:23][cH:24]2)[C:4](=[O:25])[N:3]1[CH3:26]

Participants

7

Reactant 6

HCID 887MethanolHCID 923Sodium ion2×HCID 961HydroxideHCID 3438FurfurylamineHCID 28123BorohydrideHCID 16113437HCID 16113437, compound

Product 1

HCID 251263142-amino-5-[4-(difluoromethoxy)phenyl]-5-(3-{[(2-furylmethyl)-amino]methyl}phenyl)-3-methyl-3,5-dihydro-4H-imidazol-4-one

Sources & evidence

ORD record
ord-d3596803e5b74d9fbfded4e8737c38d4
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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