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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 312414Generated: October 30, 2026

Chloroform → 5-chloro-N-[1-(2,5-difluorophenyl)-3-(1,3-dioxoisoindol-2-yl)propan-2-yl]-4-(2-methylpyrazol-3-yl)thiophene-2-carboxamide

https://huagongshe.com/reaction/312414

Reaction equation

Participants

RoleNameHCIDCharge
ReactantChloroformHCID 6212—
ReactantDiisopropylethylamineHCID 81531—
Reactant2,6-DifluorophenylalanineHCID 2737043—
Reactant5-chloro-4-(1-methyl-1H-pyrazol-5-yl)thiophene-2-carboxylic acidHCID 57826389—
ReactantHCID 178510837HCID 178510837—
Product5-chloro-N-[1-(2,5-difluorophenyl)-3-(1,3-dioxoisoindol-2-yl)propan-2-yl]-4-(2-methylpyrazol-3-yl)thiophene-2-carboxamideHCID 178481796—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (8/10)
ORD IDord-428ec296caa740cbbf848e9e94704297
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (8/10)