Hydrochloric Acid → (3-{[5-(4-Hydroxyphenyl)-6-phenylfuro[2,3-d]pyrimidin-4-yl]amino}phenoxy)acetic acid

HRID 312739Notes

Reaction equation

HRID 312739 reaction equation
[B:1]([Br:2])([Br:3])[Br:4].[CH3:5][O:6][c:7]1[cH:8][cH:9][c:10](-[c:13]2[c:14](-[c:34]3[cH:35][cH:36][cH:37][cH:38][cH:39]3)[o:15][c:16]3[n:17][cH:18][n:19][c:20]([NH:22][c:23]4[cH:24][c:25]([O:26][CH2:27][C:28](=[O:29])[OH:30])[cH:31][cH:32][cH:33]4)[c:21]23)[cH:11][cH:12]1.[Cl:41][CH2:42][Cl:43].[ClH:40]>>[OH:6][c:7]1[cH:8][cH:9][c:10](-[c:13]2[c:14](-[c:34]3[cH:35][cH:36][cH:37][cH:38][cH:39]3)[o:15][c:16]3[n:17][cH:18][n:19][c:20]([NH:22][c:23]4[cH:24][c:25]([O:26][CH2:27][C:28](=[O:29])[OH:30])[cH:31][cH:32][cH:33]4)[c:21]23)[cH:11][cH:12]1

Participants

5

Reactant 4

HCID 313Hydrochloric AcidHCID 6344DichloromethaneHCID 25134Boron tribromideHCID 582800653-{[5-(4-Methoxyphenyl)-6-phenylfuro[2,3-d]pyrimidin-4-yl]amino}phenoxyacetic acid

Product 1

HCID 25095119(3-{[5-(4-Hydroxyphenyl)-6-phenylfuro[2,3-d]pyrimidin-4-yl]amino}phenoxy)acetic acid

Sources & evidence

ORD record
ord-416577b7cc6f456999b958bbd8dbc724
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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