Hydrochloric Acid → N-(2-fluoro-4-chloro-5-cyclopentyloxyphenyl)-3,4,5,6-tetrahydrophthalimide

HRID 312967Notes

Reaction equation

HRID 312967 reaction equation
[C:27](=[O:28])([O-:29])[O-:30].[CH3:34][C:35]#[N:36].[CH:1]1([Br:6])[CH2:2][CH2:3][CH2:4][CH2:5]1.[ClH:33].[F:7][c:8]1[c:9]([N:16]2[C:17](=[O:26])[C:18]3=[C:19]([C:20]2=[O:21])[CH2:22][CH2:23][CH2:24][CH2:25]3)[cH:10][c:11]([OH:15])[c:12]([Cl:14])[cH:13]1.[K+:31].[K+:32]>>[CH:1]1([O:15][c:11]2[cH:10][c:9]([N:16]3[C:17](=[O:26])[C:18]4=[C:19]([C:20]3=[O:21])[CH2:22][CH2:23][CH2:24][CH2:25]4)[c:8]([F:7])[cH:13][c:12]2[Cl:14])[CH2:2][CH2:3][CH2:4][CH2:5]1

Participants

7

Reactant 6

HCID 313Hydrochloric AcidHCID 813Potassium Cation2×HCID 6342AcetonitrileHCID 8728BromocyclopentaneHCID 19660Carbonate IonHCID 1586511H-Isoindole-1,3(2H)-dione, 2-(4-chloro-2-fluoro-5-hydroxyphenyl)-4,5,6,7-tetrahydro-

Product 1

HCID 15279390N-(2-fluoro-4-chloro-5-cyclopentyloxyphenyl)-3,4,5,6-tetrahydrophthalimide

Sources & evidence

ORD record
ord-a8704b1c5d0743c283f31b137099512d
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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