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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 313270Generated: October 29, 2026

Hydrochloric Acid → 3-(4'-Chloro-6-fluoro-4-methyl-biphenyl-3-yl)-4-hydroxy-8-methoxy-1,8-diazaspiro[4.5]dec-3-en-2-one

https://huagongshe.com/reaction/313270

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantSodium ionHCID 923—
ReactantWaterHCID 962—
Reactant1,2-DimethoxyethaneHCID 8071—
ReactantCarbonate IonHCID 19660—
Reactant4-Chlorophenylboronic acidHCID 74299—
Reactant3-(5-Bromo-4-fluoro-2-methyl-phenyl)-4-hydroxy-8-methoxy-1,8-diazaspiro[4.5]dec-3-en-2-oneHCID 59614597—
ReactantHCID 178420554HCID 178420554—
Product3-(4'-Chloro-6-fluoro-4-methyl-biphenyl-3-yl)-4-hydroxy-8-methoxy-1,8-diazaspiro[4.5]dec-3-en-2-oneHCID 59614583—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (8/10)
ORD IDord-5340ee477aa04158a3f731903ff6d641
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (8/10)