Benzenamine, 3-ethynyl- → Hydrochloric Acid

HRID 313329Notes

Reaction equation

HRID 313329 reaction equation
[C:21](#[CH:22])[c:23]1[cH:24][c:25]([NH2:26])[cH:27][cH:28][cH:29]1.[Cl:1][c:2]1[n:3][cH:4][n:5][c:6]2[cH:7][c:8]([O:17][CH2:18][CH2:19][Cl:20])[c:9]([O:12][CH2:13][CH2:14][O:15][CH3:16])[cH:10][c:11]12>>[ClH:1].[c:2]1([NH:26][c:25]2[cH:24][c:23]([C:21]#[CH:22])[cH:29][cH:28][cH:27]2)[n:3][cH:4][n:5][c:6]2[cH:7][c:8]([O:17][CH2:18][CH2:19][Cl:20])[c:9]([O:12][CH2:13][CH2:14][O:15][CH3:16])[cH:10][c:11]12

Participants

4

Reactant 2

HCID 104682Benzenamine, 3-ethynyl-HCID 189250914-Chloro-7-(2-chloroethoxy)-6-(2-methoxyethoxy)quinazoline

Product 2

HCID 313Hydrochloric AcidHCID 16045728Erlotinib impurity A

Sources & evidence

ORD record
ord-465cd8f04e6c45c0b776bb62464487de
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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