Dichloromethane → 2,4-dichloro-N-{4-cyclopropanecarbonyl-5-[4-(piperidine-1-sulfonyl)-phenylsulfanyl]-pyridin-2-yl}-benzenesulfonamide

HRID 313349Notes

Reaction equation

HRID 313349 reaction equation
[CH3:43][CH2:44][O:45][C:46](=[O:47])[CH3:48].[Cl:1][c:2]1[c:3]([S:9](=[O:10])(=[O:11])[NH:12][c:13]2[n:14][cH:15][c:16]([S:24][c:25]3[cH:26][cH:27][c:28]([S:31](=[O:32])(=[O:33])[N:34]4[CH2:35][CH2:36][CH2:37][CH2:38][CH2:39]4)[cH:29][cH:30]3)[c:17]([CH:19]([OH:20])[CH:21]3[CH2:22][CH2:23]3)[cH:18]2)[cH:4][cH:5][c:6]([Cl:8])[cH:7]1.[Cl:40][CH2:41][Cl:42]>>[Cl:1][c:2]1[c:3]([S:9](=[O:10])(=[O:11])[NH:12][c:13]2[n:14][cH:15][c:16]([S:24][c:25]3[cH:26][cH:27][c:28]([S:31](=[O:32])(=[O:33])[N:34]4[CH2:35][CH2:36][CH2:37][CH2:38][CH2:39]4)[cH:29][cH:30]3)[c:17]([C:19](=[O:20])[CH:21]3[CH2:22][CH2:23]3)[cH:18]2)[cH:4][cH:5][c:6]([Cl:8])[cH:7]1

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 8857Ethyl AcetateHCID 577182332,4-dichloro-N-{4-(cyclopropyl-hydroxy-methyl)-5-[4-(piperidine-1-sulfonyl)-phenylsulfanyl]-pyridin-2-yl}-benzenesulfonamide

Product 1

HCID 577182852,4-dichloro-N-{4-cyclopropanecarbonyl-5-[4-(piperidine-1-sulfonyl)-phenylsulfanyl]-pyridin-2-yl}-benzenesulfonamide

Sources & evidence

ORD record
ord-49822305f63a487fb9dbe112f90745ac
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

Loading…