Potassium Cation → N-[4-[1-(2-methoxyphenyl)-4-piperazinylmethyl]phenyl]-7-(4-methylphenyl)-3,4-dihydronaphthalene-2-carboxamide

HRID 313560Notes

Reaction equation

HRID 313560 reaction equation
[C:43](=[O:44])([O-:45])[O-:46].[CH3:29][O:30][c:31]1[c:32]([N:37]2[CH2:38][CH2:39][NH:40][CH2:41][CH2:42]2)[cH:33][cH:34][cH:35][cH:36]1.[Cl:1][CH2:2][c:3]1[cH:4][cH:5][c:6]([NH:9][C:10](=[O:11])[C:12]2=[CH:13][c:14]3[cH:15][c:16](-[c:22]4[cH:23][cH:24][c:25]([CH3:28])[cH:26][cH:27]4)[cH:17][cH:18][c:19]3[CH2:20][CH2:21]2)[cH:7][cH:8]1.[K+:47].[K+:48].[O:50]=[CH:51][N:52]([CH3:53])[CH3:54].[OH2:49]>>[CH2:2]([c:3]1[cH:4][cH:5][c:6]([NH:9][C:10](=[O:11])[C:12]2=[CH:13][c:14]3[cH:15][c:16](-[c:22]4[cH:23][cH:24][c:25]([CH3:28])[cH:26][cH:27]4)[cH:17][cH:18][c:19]3[CH2:20][CH2:21]2)[cH:7][cH:8]1)[N:40]1[CH2:39][CH2:38][N:37]([c:32]2[c:31]([O:30][CH3:29])[cH:36][cH:35][cH:34][cH:33]2)[CH2:42][CH2:41]1

Participants

7

Reactant 6

HCID 813Potassium Cation2×HCID 962WaterHCID 13461-(2-Methoxyphenyl)piperazineHCID 6228DimethylformamideHCID 19660Carbonate IonHCID 18472361N-[4-(chloromethyl)phenyl]-7-(4-methylphenyl)-3,4-dihydronaphthalene-2-carboxamide

Product 1

HCID 54091321N-[4-[1-(2-methoxyphenyl)-4-piperazinylmethyl]phenyl]-7-(4-methylphenyl)-3,4-dihydronaphthalene-2-carboxamide

Sources & evidence

ORD record
ord-caf48e8c3b2a4b6fa64cee267c863635
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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