Potassium Cation → (-)-4-{2-[2-(4-Chloro-phenyl)-5,6-difluoro-benzoimidazol-1-yl]-2-cyclohexyl-1,1-dimethyl-ethoxy}-benzonitrile
Reaction equation
[CH3:39][Si:40]([N-:41][Si:42]([CH3:43])([CH3:44])[CH3:45])([CH3:46])[CH3:47].[Cl:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[n:9][c:10]3[c:11]([n:12]2[CH:13]([C:14]([CH3:15])([OH:16])[CH3:17])[CH:18]2[CH2:19][CH2:20][CH2:21][CH2:22][CH2:23]2)[cH:24][c:25]([F:29])[c:26]([F:28])[cH:27]3)[cH:6][cH:7]1.[F:30][c:31]1[cH:32][cH:33][c:34]([C:35]#[N:36])[cH:37][cH:38]1.[K+:48].[O:49]1[CH2:50][CH2:51][CH2:52][CH2:53]1>>[Cl:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[n:9][c:10]3[c:11]([n:12]2[CH:13]([C:14]([CH3:15])([O:16][c:31]2[cH:32][cH:33][c:34]([C:35]#[N:36])[cH:37][cH:38]2)[CH3:17])[CH:18]2[CH2:19][CH2:20][CH2:21][CH2:22][CH2:23]2)[cH:24][c:25]([F:29])[c:26]([F:28])[cH:27]3)[cH:6][cH:7]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-fdf9237bf5ac456996e03eea52b31425
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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