Dichloromethane → 3-(4-{[(2-(2,4-Dimethylphenyl)amino-2-oxoethyl)(2-furylmethyl)amino]methyl}-phenyl)-2,2-dimethylpropionic acid

HRID 313860Notes

Reaction equation

HRID 313860 reaction equation
[CH3:1][c:2]1[c:3]([NH:9][C:10]([CH2:11][N:12]([CH2:13][c:14]2[o:15][cH:16][cH:17][cH:18]2)[CH2:19][c:20]2[cH:21][cH:22][c:23]([CH2:26][C:27]([C:28](=[O:29])[O:30][C:31]([CH3:32])([CH3:33])[CH3:34])([CH3:35])[CH3:36])[cH:24][cH:25]2)=[O:37])[cH:4][cH:5][c:6]([CH3:8])[cH:7]1.[Cl:45][CH2:46][Cl:47].[OH:38][C:39]([C:40]([F:41])([F:42])[F:43])=[O:44]>>[CH3:1][c:2]1[c:3]([NH:9][C:10]([CH2:11][N:12]([CH2:13][c:14]2[o:15][cH:16][cH:17][cH:18]2)[CH2:19][c:20]2[cH:21][cH:22][c:23]([CH2:26][C:27]([C:28](=[O:29])[OH:30])([CH3:35])[CH3:36])[cH:24][cH:25]2)=[O:37])[cH:4][cH:5][c:6]([CH3:8])[cH:7]1

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 22708241Tert-butyl 3-(4-{[(2-(2,4-dimethylphenyl)amino-2-oxoethyl)(2-furylmethyl)amino]methyl}phenyl)-2,2-dimethylpropionate

Product 1

HCID 227081953-(4-{[(2-(2,4-Dimethylphenyl)amino-2-oxoethyl)(2-furylmethyl)amino]methyl}-phenyl)-2,2-dimethylpropionic acid

Sources & evidence

ORD record
ord-2612ad2466194ac89ec67f8ccc639e4c
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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