Dimethylformamide → 6-bromo-4-(4-methoxy-benzyl)-4H-pyrido[3,2-b][1,4]oxazin-3-one

HRID 313879Notes

Reaction equation

HRID 313879 reaction equation
[Br:1][c:2]1[cH:3][cH:4][c:5]2[c:10]([n:11]1)[NH:9][C:8](=[O:12])[CH2:7][O:6]2.[C:23](=[O:24])([O-:25])[O-:26].[CH3:13][O:14][c:15]1[cH:16][cH:17][c:18]([CH2:19][Cl:20])[cH:21][cH:22]1.[Cs+:27].[Cs+:28].[O:29]=[CH:30][N:31]([CH3:32])[CH3:33]>>[Br:1][c:2]1[cH:3][cH:4][c:5]2[c:10]([n:11]1)[N:9]([CH2:19][c:18]1[cH:17][cH:16][c:15]([O:14][CH3:13])[cH:22][cH:21]1)[C:8](=[O:12])[CH2:7][O:6]2

Participants

6

Reactant 5

HCID 6228DimethylformamideHCID 19660Carbonate IonHCID 699934-Methyloxybenzyl chlorideHCID 104967Cesium cation2×HCID 218737726-Bromo-2H-pyrido[3,2-B][1,4]oxazin-3(4H)-one

Product 1

HCID 866493756-bromo-4-(4-methoxy-benzyl)-4H-pyrido[3,2-b][1,4]oxazin-3-one

Sources & evidence

ORD record
ord-4ec88ec4e1ec445dba1a82debc955f6f
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

Loading…