Hydrochloric Acid → 6-Fluoro-2-phenyl-[1,2,4]triazolo[1,5-a]pyridin-7-amine

HRID 313958Notes

Reaction equation

[ClH:25].[F:1][c:2]1[c:3]([NH:17][C:18](=[O:19])[O:20][C:21]([CH3:22])([CH3:23])[CH3:24])[cH:4][c:5]2[n:6]([cH:7]1)[n:8][c:9](-[c:11]1[cH:12][cH:13][cH:14][cH:15][cH:16]1)[n:10]2.[Na+:26].[Na+:27].[O-:28][C:29](=[O:30])[O-:31]>>[F:1][c:2]1[c:3]([NH2:17])[cH:4][c:5]2[n:6]([cH:7]1)[n:8][c:9](-[c:11]1[cH:12][cH:13][cH:14][cH:15][cH:16]1)[n:10]2

Participants

Reactant 4

HCID 313Hydrochloric Acid

HCID 923Sodium ion2×

HCID 19660Carbonate Ion

HCID 67776795Tert-butyl 6-fluoro-2-phenyl-[1,2,4]triazolo[1,5-a]pyridin-7-ylcarbamate

Product 1

HCID 677751876-Fluoro-2-phenyl-[1,2,4]triazolo[1,5-a]pyridin-7-amine

Sources & evidence

ORD record: ord-9b853e6be3d04328ac0cda7ce5500808
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (8/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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